YS-49 monohydrate
Product Specifications
Target
Akt, RAAS, Others, PI3K, Adrenergic Receptor
Related Pathways
GPCR/G Protein, Cytoskeletal Signaling, Endocrinology/Hormones, Neuroscience, PI3K/Akt/mTOR signaling, Others
Bioactivity
YS-49 (monohydrate) is an isoquinoline compound alkaloid that functions as a PI3K/Akt activator, specifically targeting a downstream effect of RhoA, to mitigate the activation of RhoA/PTEN in 3-methylcholanthrene-treated cells. It also prevents the angiotensin II (Ang II) -induced proliferation of vascular smooth muscle cells (VSMCs) by promoting the expression of heme oxygenase (HO) -1. Additionally, YS-49 exerts a significant positive inotropic effect by stimulating cardiac β-adrenoceptors, showcasing its multifaceted pharmacological activities [1] [2] [3].
Molecular Formula
C20H22BrNO3
Molecular Weight
404.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6276686-01 0.1 mL
ATP6V1B1, ID (ATP6V1B1, ATP6B1, VATB, VPP3, V-type proton ATPase subunit B, kidney isoform, Endomembrane proton pump 58kD subunit, Vacuolar proton pump subunit B 1) (MaxLight 650)
Sign In for Pricing
View Details MBS6276686-02 5x 0.1 mL
ATP6V1B1, ID (ATP6V1B1, ATP6B1, VATB, VPP3, V-type proton ATPase subunit B, kidney isoform, Endomembrane proton pump 58kD subunit, Vacuolar proton pump subunit B 1) (MaxLight 650)
Sign In for Pricing
View Details 
