Flumethasone pivalate

Flumethasone pivalate is a glucocorticoid corticosteroid and a corticosteroid ester. Flumetasone pivalate has anti-inflammatory, antipruritic, and vasoconstrictive activities[1].

Product Specifications

CAS Number

[2002-29-1]

Product Name Alternative

Flumethasone 21-pivalate; Locacorten; Locorten

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Glucocorticoid Receptor

Type

Reference compound

Related Pathways

Immunology/Inflammation; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/flumethasone-pivalate.html

Purity

98.17

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@](C[C@@H](C)[C@]2(O)C(COC(C(C)(C)C)=O)=O)([H])[C@@]3([H])[C@@](F)([C@@]4(C([C@@H](F)C3)=CC(C=C4)=O)C)[C@@H](O)C1

Molecular Formula

C27H36F2O6

Molecular Weight

494.57

Precautions

H302, H315, H319, H335

References & Citations

[1]Mandour, A.A., et al. Review on analytical studies of some pharmaceutical compounds containing heterocyclic rings: brinzolamide, timolol maleate, flumethasone pivalate, and clioquinol. Futur J Pharm Sci 6, 52 (2020) .