What is the catalog number for ARC19499?

The catalog number for ARC19499 is T75152.

What sizes are available for ARC19499?

ARC19499 is available in the following size(s): 5 mg, 50 mg.

How many pack sizes does ARC19499 come in?

ARC19499 is available in 2 different pack sizes.

Is ARC19499 in stock?

ARC19499 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ARC19499?

ARC19499 is manufactured by Molfinity.

What is the estimated delivery time for ARC19499?

Estimated delivery time for ARC19499 is approximately 10 business day(s), depending on your location.

ARC19499

Product Specifications

CAS Number

1350667-54-7

Target

Others, Factor VIIa, Factor Xa

Related Pathways

Metabolism, Others

Bioactivity

ARC19499, an aptamer, inhibits the tissue factor pathway inhibitor (TFPI), facilitating clot initiation and propagation through the extrinsic pathway. It binds specifically to TFPI, blocking its inhibition of both factor Xa and the TF/factor VIIa complex, thereby correcting thrombin generation in hemophilia A and B plasma and restoring clotting in FVIII-neutralized whole blood.