CPD-1224
Product Specifications
CAS Number
2891620-68-9
Target
Others, ALK
Related Pathways
Others, Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
CPD-1224, an orally active derivative that binds cereblon ligands to ALK inhibitors, specifically targets and degrades EML4-ALK oncogenic fusions, including ALK and its mutants L1196M/G1202R.
Smiles
O=C1C2=CC=C(C=C2C(=O)N1C3C(=O)NC(=O)CC3)N4CC(C4)CN5CCC(C6=CC(OC)=C(C=C6C)NC7=NC=C(Cl)C(=N7)NC=8C=CC=CC8S(=O)(=O)C(C)C)CC5
Molecular Formula
C43H47ClN8O7S
Molecular Weight
855.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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