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CPD-1224

Product Specifications

CAS Number

2891620-68-9

Target

Others, ALK

Related Pathways

Others, Tyrosine Kinase/Adaptors, Angiogenesis

Bioactivity

CPD-1224, an orally active derivative that binds cereblon ligands to ALK inhibitors, specifically targets and degrades EML4-ALK oncogenic fusions, including ALK and its mutants L1196M/G1202R.

Smiles

O=C1C2=CC=C(C=C2C(=O)N1C3C(=O)NC(=O)CC3)N4CC(C4)CN5CCC(C6=CC(OC)=C(C=C6C)NC7=NC=C(Cl)C(=N7)NC=8C=CC=CC8S(=O)(=O)C(C)C)CC5

Molecular Formula

C43H47ClN8O7S

Molecular Weight

855.4

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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