Luxdegalutamide
Product Specifications
CAS Number
2750830-09-0
Target
PROTACs, Androgen Receptor
Related Pathways
PROTAC, Endocrinology/Hormones
Purity
>99.99%
Bioactivity
Luxdegalutamide (ARV-766) is a novel, potent, and orally bioavailable proteolytic targeting chimera (PROTAC) protein degrader that degrades not only wild-type AR but also clinically relevant AR LBD mutants, including the most prevalent AR L702H, H875Y, and T878A mutations.
Smiles
O([C@H]1C(C)(C)[C@H](NC(=O)C2=CC=C(C=C2)N3CCC(CN4CCN(CC4)C5=CC(F)=C(C(N[C@@H]6C(=O)NC(=O)CC6)=O)C=C5)CC3)C1(C)C)C7=CC(OC)=C(C#N)C=C7
Molecular Formula
C45H54FN7O6
Molecular Weight
807.95
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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