ITK degrader 2
Product Specifications
CAS Number
2858738-65-3
Target
Tyrosine Kinases|||Others|||PROTACs
Related Pathways
Tyrosine Kinase/Adaptors|||PROTAC|||Others
Bioactivity
ITK Degrader 2 (Compound 30) functions as a modulator for targeted ubiquitination and serves as a molecule for targeted protein degradation, specifically degrading ITK [1].
Smiles
C[C@@]12[C@@](C1(F)F)(CC3=C(C2)NN=C3C=4NC=5C(C4)=CC=C(N(C([C@H](C)N6CCN(CC7CCN(CC7)C8=CC=C(C=N8)C9C(=O)NC(=O)CC9)CC6)=O)C)C5)[H]
Molecular Formula
C41H49F2N9O3
Molecular Weight
753.88
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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SLC9A3R2 (E3KARP, HGNC:11076, isoform 3 regulator 2, isoform 3 Regulatory Factor 2, MGC104639, Na (+) /H (+) exchange Regulatory coFactor NHE RF2, Na (+) /H (+) exchange Regulatory coFactor NHE-RF2, NHE3 Kinase A Regulatory Protein)
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