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Trametiglue

Product Specifications

CAS Number

2666940-97-0

Target

MEK, Others

Related Pathways

MAPK, Others

Bioactivity

Trametiglue, a Trametinib derivative, exhibits exceptional potency and selectivity in targeting KSR-MEK and RAF-MEK through distinctive interfacial binding interactions [1].

Smiles

CC1=C2C(=C(NC3=C(F)C=C(I)C=C3)N(C)C1=O)C(=O)N(C(=O)N2C4=CC(NS(NC)(=O)=O)=CC=C4)C5CC5

Molecular Formula

C25H24FIN6O5S

Molecular Weight

666.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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