PROTAC STAT3 degrader-2
Product Specifications
CAS Number
2429877-78-9
Target
Others, PROTACs, STAT
Related Pathways
JAK/STAT signaling, Others, Stem Cells, PROTAC
Bioactivity
PROTAC STAT3 degrader-2 is a selective and effective PROTAC degrader of the STAT3 protein, exhibiting a DC50 of 3.54 μM in Molm-16 cells. It holds potential for cancer research [1].
Smiles
O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2C#CCCCCCC(=O)N4C[C@H](NC(=O)C5=CC=6C(N5)=CC=C(C(P(=O)(O)O)(F)F)C6)C(=O)N7[C@@](CC4)(CC[C@H]7C(N[C@H](C(NC(C8=CC=CC=C8)C9=CC=CC=C9)=O)CCC(N)=O)=O)[H]
Molecular Formula
C59H60F2N9O13P
Molecular Weight
1172.13
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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