STING agonist-28
Product Specifications
CAS Number
2868261-50-9
Target
STING|||Others
Related Pathways
Others|||Immunology/Inflammation
Bioactivity
STING agonist-23 (CF510) is a non-nucleotide, small-molecule activator of the STING pathway. It initiates the phosphorylation of STING, TBK1, and IRF3, enhancing the production of IFN-?, IL-6, CXCL-10, TNF-?, ISG-15, and CCL-5 in tumor cells. Notably, it demonstrates activity against SARS-CoV series strains [1].
Smiles
C(/C=C/CN1C=2C(N=C1NC(=O)C=3N(CC)N=C(C)C3)=CC(C(N)=O)=CN2)N4C=5C(N=C4NC(=O)C=6N(CC)N=C(C)C6)=CC(C(N)=O)=CC5OCCN7CCOCC7
Molecular Formula
C39H46N14O6
Molecular Weight
806.87
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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