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STING agonist-25

Product Specifications

CAS Number

2408723-10-2

Target

Others, STING

Related Pathways

Immunology/Inflammation, Others

Bioactivity

STING agonist-23 (CF505) is a non-nucleotide, small-molecule compound that stimulates STING, enhancing the phosphorylation of STING, TBK1, and IRF3. It elevates the production of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 in tumor cells and demonstrates efficacy against SARS-CoV strains [1].

Smiles

C(/C=C/CN1C=2C(N=C1NC(=O)C=3N(CC)N=C(C)C3)=CC(C(N)=O)=CN2)N4C=5C(N=C4NC(=O)C=6N(CC)N=C(C)C6)=CC(C(N)=O)=CC5OCCCO

Molecular Formula

C36H41N13O6

Molecular Weight

751.79

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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