STING agonist-25
Product Specifications
CAS Number
2408723-10-2
Target
Others|||STING
Related Pathways
Immunology/Inflammation|||Others
Bioactivity
STING agonist-23 (CF505) is a non-nucleotide, small-molecule compound that stimulates STING, enhancing the phosphorylation of STING, TBK1, and IRF3. It elevates the production of IFN-?, IL-6, CXCL-10, TNF-?, ISG-15, and CCL-5 in tumor cells and demonstrates efficacy against SARS-CoV strains [1].
Smiles
C(/C=C/CN1C=2C(N=C1NC(=O)C=3N(CC)N=C(C)C3)=CC(C(N)=O)=CN2)N4C=5C(N=C4NC(=O)C=6N(CC)N=C(C)C6)=CC(C(N)=O)=CC5OCCCO
Molecular Formula
C36H41N13O6
Molecular Weight
751.79
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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