STING agonist-24
Product Specifications
CAS Number
2408722-91-6
Target
Others|||STING
Related Pathways
Immunology/Inflammation|||Others
Bioactivity
STING agonist-24 (CF504), a non-nucleotide small-molecule STING agonist, activates STING, leading to increased phosphorylation of STING, TBK1, and IRF3. It elevates levels of IFN-?, IL-6, CXCL-10, TNF-?, ISG-15, and CCL-5 in tumor cells, demonstrating activity against SARS-CoV series strains [1].
Smiles
C(/C=C/CN1C=2C(N=C1NC(=O)C=3N(CC)N=C(C)C3)=CC(C(N)=O)=CN2)N4C=5C(N=C4NC(=O)C=6N(CC)N=C(C)C6)=CC(C(N)=O)=CC5OC
Molecular Formula
C34H37N13O5
Molecular Weight
707.74
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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