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STING agonist-24

Product Specifications

CAS Number

2408722-91-6

Target

Others|||STING

Related Pathways

Immunology/Inflammation|||Others

Bioactivity

STING agonist-24 (CF504), a non-nucleotide small-molecule STING agonist, activates STING, leading to increased phosphorylation of STING, TBK1, and IRF3. It elevates levels of IFN-?, IL-6, CXCL-10, TNF-?, ISG-15, and CCL-5 in tumor cells, demonstrating activity against SARS-CoV series strains [1].

Smiles

C(/C=C/CN1C=2C(N=C1NC(=O)C=3N(CC)N=C(C)C3)=CC(C(N)=O)=CN2)N4C=5C(N=C4NC(=O)C=6N(CC)N=C(C)C6)=CC(C(N)=O)=CC5OC

Molecular Formula

C34H37N13O5

Molecular Weight

707.74

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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