PROTAC TYK2 degradation agent1
Product Specifications
CAS Number
2921556-14-9
Target
PROTACs, JAK
Related Pathways
JAK/STAT signaling, PROTAC, Chromatin/Epigenetic, Stem Cells, Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
PROTAC TYK2 Degradation Agent1 is a potent, subtype-selective degrader of TYK2, exhibiting degradation activity with a DC50 of 14 nM. It is utilized in autoimmune disease research [1].
Smiles
O(C)C1=C(C=CC=C1NC=2C(C(NC)=O)=CN=C(NC3=CC=C(C(NCCCCCCCCCC(N[C@H](C(=O)N4[C@H](C(NCC5=CC=C(C=C5)C6=C(C)N=CS6)=O)C[C@@H](O)C4)C(C)(C)C)=O)=O)C=N3)C2)C=7N=CN(C)N7
Molecular Formula
C55H69N13O7S
Molecular Weight
1056.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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