PROTAC HDAC6 degrader 1
Product Specifications
CAS Number
2785404-76-2
Target
HDAC|||Others|||Apoptosis|||PROTACs
Related Pathways
Apoptosis|||Others|||DNA Damage/DNA Repair|||Chromatin/Epigenetic|||PROTAC
Bioactivity
Compound A6, a potent and selective PROTAC HDAC6 degrader, exhibits a DC50 of 3.5 nM. It demonstrates notable antiproliferative activity by inducing apoptosis in myeloid leukemia cell lines [1].
Smiles
O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2OCC(NCCCCCCCC(NC4=CC=C(C(NCCCCCCC(NO)=O)=O)C=C4)=O)=O
Molecular Formula
C37H46N6O10
Molecular Weight
734.8
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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