STING-IN-5

STING-IN-5, a potent inhibitor of the Stimulator of Interferon Genes (STING) pathway, significantly suppresses lipopolysaccharide (LPS) -induced nitric oxide (NO) synthesis in macrophages, exhibiting an IC50 of 1.15 ?M. This compound dampens the inflammatory response and offers potential for research into anti-inflammatory diseases and sepsis [1].