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Zn-DPA-maytansinoid conjugate 1

Product Specifications

Target

CCR|||CXCR|||Others|||STAT|||Chk

Related Pathways

GPCR/G Protein|||Stem Cells|||Others|||Immunology/Inflammation|||Microbiology/Virology|||JAK/STAT signaling|||Autophagy|||Cell Cycle/Checkpoint

Bioactivity

Zn-DPA-maytansinoid conjugate 1, a small molecule-based immune checkpoint-targeting maytansinoid conjugate, effectively induces sustained tumor growth regression and transforms the tumor microenvironment (TME) into an "inflamed hot tumor" [1].

Molecular Formula

C115H145ClN18O31S2Zn2

Molecular Weight

2505.83

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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