PROTAC CDK9 degrader-6
Product Specifications
CAS Number
2935587-91-8
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
PROTAC CDK9 degrader-6 is a specific PROTAC targeting CDK9 for degradation via the proteasome pathway, effectively degrading CDK9 with DC50 values of 0.10 μM and 0.14 μM for the CDK9 42 and CDK9 55 isoforms, respectively [1].
Smiles
O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCC(NCCCCCCCCCCC(=O)N4CCC(NC(=O)C=5C(NC(=O)C6=C(Cl)C=CC=C6Cl)=CNN5)CC4)=O
Molecular Formula
C42H49Cl2N9O8
Molecular Weight
878.8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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