Anticancer agent 114
Product Specifications
Target
Others, Proteasome
Related Pathways
Ubiquitination, Others, Proteases/Proteasome
Bioactivity
Anticancer agent 114, a dipeptide boronic acid ester, functions as a potent proteasome inhibitor with an oral activity and demonstrates an IC50 of 2.2 nM. It exhibits antiproliferative properties specifically targeting RPMI-8226 cells, making it valuable for research into multiple myeloma [1].
Molecular Formula
C28H33BF6N2O7
Molecular Weight
634.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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