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Anticancer agent 114

Product Specifications

Target

Others, Proteasome

Related Pathways

Ubiquitination, Others, Proteases/Proteasome

Bioactivity

Anticancer agent 114, a dipeptide boronic acid ester, functions as a potent proteasome inhibitor with an oral activity and demonstrates an IC50 of 2.2 nM. It exhibits antiproliferative properties specifically targeting RPMI-8226 cells, making it valuable for research into multiple myeloma [1].

Molecular Formula

C28H33BF6N2O7

Molecular Weight

634.37

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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