S1R agonist 1
Product Specifications
CAS Number
193354-70-0
Target
Others, Sigma receptor
Related Pathways
GPCR/G Protein, Others
Bioactivity
Compound 6b, also known as S1R agonist 1, is a selective agonist for S1R with dissociation constants (Ki) of 0.93 nM for S1R and 72 nM for S2R. This compound demonstrates neuroprotective effects against reactive oxygen species (ROS) and NMDA-induced neurotoxicity [1].
Smiles
C(C1CCN(CCOC2=CC=CC=C2)CC1)C3=CC=CC=C3
Molecular Formula
C20H25NO
Molecular Weight
295.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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