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S1R agonist 1

Product Specifications

CAS Number

193354-70-0

Target

Others, Sigma receptor

Related Pathways

GPCR/G Protein, Others

Bioactivity

Compound 6b, also known as S1R agonist 1, is a selective agonist for S1R with dissociation constants (Ki) of 0.93 nM for S1R and 72 nM for S2R. This compound demonstrates neuroprotective effects against reactive oxygen species (ROS) and NMDA-induced neurotoxicity [1].

Smiles

C(C1CCN(CCOC2=CC=CC=C2)CC1)C3=CC=CC=C3

Molecular Formula

C20H25NO

Molecular Weight

295.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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