What is the catalog number for PKM2/PDK1-IN-1?

The catalog number for PKM2/PDK1-IN-1 is T74814.

What sizes are available for PKM2/PDK1-IN-1?

PKM2/PDK1-IN-1 is available in the following size(s): 5 mg, 50 mg.

How many pack sizes does PKM2/PDK1-IN-1 come in?

PKM2/PDK1-IN-1 is available in 2 different pack sizes.

Is PKM2/PDK1-IN-1 in stock?

PKM2/PDK1-IN-1 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PKM2/PDK1-IN-1?

PKM2/PDK1-IN-1 is manufactured by Molfinity.

What is the estimated delivery time for PKM2/PDK1-IN-1?

Estimated delivery time for PKM2/PDK1-IN-1 is approximately 10 business day(s), depending on your location.

PKM2/PDK1-IN-1

Product Specifications

Target

PDK, PKM, Others, Apoptosis, Akt, EGFR

Related Pathways

Apoptosis, Others, PI3K/Akt/mTOR signaling, Angiogenesis, Cytoskeletal Signaling, JAK/STAT signaling, Metabolism, Tyrosine Kinase/Adaptors

Bioactivity

PKM2/PDK1-IN-1, a shikonin thioether derivative, serves as a dual inhibitor for PKM2/PDK1. This compound effectively inhibits the proliferation and induces apoptosis in NSCLC cells. It promotes intercellular ROS production and modulates apoptotic proteins, engaging in both mitochondrial and death receptor pathways [1].