HBChE-IN-1
Product Specifications
CAS Number
1776948-12-9
Target
Others, Microtubule Associated, Cholinesterase (ChE), Beta Amyloid
Related Pathways
Cytoskeletal Signaling, Others, Neuroscience
Bioactivity
HBChE-IN-1 (compound 4), a quinolizidinyl derivative, effectively inhibits human Butyrylcholinesterase (hBChE) with an IC50 value of 7 nM, demonstrating high selectivity against human Acetylcholinesterase (hAChE) . It also inhibits tau and Aβ 40 protein aggregation, with IC50 values of 20 and 4.3 μM, respectively, making it valuable for Alzheimer's disease research [1].
Smiles
N(CCCSC[C@H]1[C@@]2(N(CCC1)CCCC2)[H])C3=C4C(SC=5C(C4=O)=CC=CC5)=C(C)C=C3
Molecular Formula
C27H34N2OS2
Molecular Weight
466.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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