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HBChE-IN-1

Product Specifications

CAS Number

1776948-12-9

Target

Others, Microtubule Associated, Cholinesterase (ChE), Beta Amyloid

Related Pathways

Cytoskeletal Signaling, Others, Neuroscience

Bioactivity

HBChE-IN-1 (compound 4), a quinolizidinyl derivative, effectively inhibits human Butyrylcholinesterase (hBChE) with an IC50 value of 7 nM, demonstrating high selectivity against human Acetylcholinesterase (hAChE) . It also inhibits tau and Aβ 40 protein aggregation, with IC50 values of 20 and 4.3 μM, respectively, making it valuable for Alzheimer's disease research [1].

Smiles

N(CCCSC[C@H]1[C@@]2(N(CCC1)CCCC2)[H])C3=C4C(SC=5C(C4=O)=CC=CC5)=C(C)C=C3

Molecular Formula

C27H34N2OS2

Molecular Weight

466.7

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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