USP28-IN-3
Product Specifications
CAS Number
2931509-14-5
Target
DUB
Related Pathways
Ubiquitination, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Purity
0.9992
Bioactivity
USP28-IN-3 is a highly selective USP28 inhibitor with an IC50 value of 0.1 μM against USP28.USP28-IN-3 exhibits anticancer activity and inhibits USP2, USP7, USP8, USP9x, UCHL3, and UCHL5.USP28-IN-3 is cytotoxic to human colorectal and lung squamous carcinoma cells, inhibiting c-cells and c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-cells through the ubiquitin-proteasome system. -proteasome system to dose-dependently downregulate cellular levels of c-Myc.
Smiles
O=C(NC1=CC=C(Cl)C(=C1)C=2C=CC3=C(C2)CCNC3)C4=CC=C(C=C4Cl)S(=O)(=O)C
Molecular Formula
C23H20Cl2N2O3S
Molecular Weight
475.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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