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ABBV-969 Payload

Product Specifications

CAS Number

2857037-70-6

Target

Topoisomerase|||Others|||Drug-Linker Conjugates for ADC

Related Pathways

Others|||DNA Damage/DNA Repair|||Antibody-drug Conjugate/ADC Related

Purity

0.9701

Bioactivity

ABBV-969 Payload (Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT) is a drug-linker conjugate employed in the synthesis of antibody-drug conjugates (ADCs) . The ABBV-969 Payload contains a Topoisomerase I inhibitor molecule and a chemical linker, enabling coupling with anti-c-Met antibodies to generate ABBV-969 ADCs with targeted anticancer activity.

Smiles

N(C([C@@H](NC([C@@H](NC(CBr)=O)[C@H](C)C)=O)C)=O)C12CC(C1)(C2)C3=C4C(C=5N(C4)C(=O)C6=C(C5)[C@](CC)(O)C(=O)OC6)=NC=7C3=CC8=C(C7)OCO8

Molecular Formula

C36H38BrN5O9

Molecular Weight

764.62

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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