ABBV-969 Payload
Product Specifications
CAS Number
2857037-70-6
Target
Topoisomerase|||Others|||Drug-Linker Conjugates for ADC
Related Pathways
Others|||DNA Damage/DNA Repair|||Antibody-drug Conjugate/ADC Related
Purity
0.9701
Bioactivity
ABBV-969 Payload (Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT) is a drug-linker conjugate employed in the synthesis of antibody-drug conjugates (ADCs) . The ABBV-969 Payload contains a Topoisomerase I inhibitor molecule and a chemical linker, enabling coupling with anti-c-Met antibodies to generate ABBV-969 ADCs with targeted anticancer activity.
Smiles
N(C([C@@H](NC([C@@H](NC(CBr)=O)[C@H](C)C)=O)C)=O)C12CC(C1)(C2)C3=C4C(C=5N(C4)C(=O)C6=C(C5)[C@](CC)(O)C(=O)OC6)=NC=7C3=CC8=C(C7)OCO8
Molecular Formula
C36H38BrN5O9
Molecular Weight
764.62
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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