AK-2292
Product Specifications
Target
PROTACs, STAT
Related Pathways
PROTAC, JAK/STAT signaling, Stem Cells
Bioactivity
AK-2292 is a potent and selective STAT5 PROTAC degrader with a DC50 of 0.10 μM. It induces degradation of STAT5A/B proteins in vitro and in vivo and can cause tumor regression in acute myeloid leukemia and chronic myeloid leukemia xenograft mouse models [1] [2].
Molecular Formula
C52H54F2N7O10PS2
Molecular Weight
1070.13
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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