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AK-2292

Product Specifications

Target

PROTACs, STAT

Related Pathways

PROTAC, JAK/STAT signaling, Stem Cells

Bioactivity

AK-2292 is a potent and selective STAT5 PROTAC degrader with a DC50 of 0.10 μM. It induces degradation of STAT5A/B proteins in vitro and in vivo and can cause tumor regression in acute myeloid leukemia and chronic myeloid leukemia xenograft mouse models [1] [2].

Molecular Formula

C52H54F2N7O10PS2

Molecular Weight

1070.13

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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