MTX-23
Product Specifications
CAS Number
2488296-74-6
Target
Apoptosis, PROTACs, Androgen Receptor
Related Pathways
Endocrinology/Hormones, Apoptosis, PROTAC
Bioactivity
MTX-23, an AR-targeted Proteolysis Targeting Chimera (PROTAC), effectively degrades both AR-V7 and AR-FL, inhibiting the proliferation of CaP cells and inducing apoptosis [1].
Smiles
O=C(NCCCCC(=O)N[C@@H](C(C)(C)C)C(=O)N1[C@@H](C[C@@H](O)C1)C(=O)N[C@@H](C)C2=CC=C(C=C2)C3=C(C)N=CS3)COC4=C(C=CC(F)=C4F)C5N=C(SC=5)N6CCOCC6
Molecular Formula
C43H53F2N7O7S2
Molecular Weight
882.05
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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