M47

Product Specifications

CAS Number

890808-56-7

Target

Apoptosis, p53

Related Pathways

Apoptosis

Bioactivity

M47 is a selective CRY1 (Cryptochrome 1) degradator that enhances nuclear degradation of CRY1 and disrupts its stability, thereby extending the lifespan of p53 knockout mice. It facilitates research into various cancers involving p53 mutations.

Smiles

O=C(C=1OC2=CC=C3OC(C4=CC=C(Cl)C=C4)(C)CC(=O)C3=C2C1C)N5C=6C=CC=CC6CC5

Molecular Formula

C28H22ClNO4

Molecular Weight

471.93

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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