M47
Product Specifications
CAS Number
890808-56-7
Target
Apoptosis|||p53
Related Pathways
Apoptosis
Bioactivity
M47 is a selective CRY1 (Cryptochrome 1) degradator that enhances nuclear degradation of CRY1 and disrupts its stability, thereby extending the lifespan of p53 knockout mice. It facilitates research into various cancers involving p53 mutations.
Smiles
O=C(C=1OC2=CC=C3OC(C4=CC=C(Cl)C=C4)(C)CC(=O)C3=C2C1C)N5C=6C=CC=CC6CC5
Molecular Formula
C28H22ClNO4
Molecular Weight
471.93
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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