MC-Gly-Gly-Phe-Gly- (S) -Cyclopropane-Exatecan
Product Specifications
CAS Number
2414254-52-5
Target
Drug-Linker Conjugates for ADC, Topoisomerase
Related Pathways
Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair
Bioactivity
MC-Gly-Gly-Phe-Gly- (S) -Cyclopropane-Exatecan is a agent-linker conjugates for ADC , consisting Exatecan . Exatecan is a DNA Topoisomerase I inhibitor (IC 50 =2.2 μM) [1] .
Smiles
CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CC[C@H](NC(=O)[C@@H](OCNC(=O)CNC(=O)[C@H](Cc6ccccc6)NC(=O)CNC(=O)CNC(=O)CCCCCN6C(=O)C=CC6=O)C6CC6)c(c3Cn1c2=O)c45
Molecular Formula
C55H60FN9O13
Molecular Weight
1074.12
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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