YX-2-107
Product Specifications
CAS Number
2417408-46-7
Target
CDK, PROTACs
Related Pathways
PROTAC, Cell Cycle/Checkpoint
Purity
0.99148
Bioactivity
YX-2-107 is a selective and potent CDK6-degrading PROTAC with an IC50 value of 4.4 nM.YX-2-107 inhibits RB phosphorylation and FOXM1 expression in vitro, and inhibits the development of Ph+ ALL in rats.YX-2-107 can be used for the prophylaxis and treatment of Ph chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) . YX-2-107 can be used for the prevention and treatment of Ph chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) .
Smiles
O=C1NC(=O)C(N2C(=O)C=3C=CC=C(OCC(=O)NCCCCNCC(=O)N4CCN(C5=CN=C(C=C5)NC=6N=CC7=C(N6)N(C(=O)C(C(=O)C)=C7C)C8CCCC8)CC4)C3C2=O)CC1
Molecular Formula
C45H51N11O9
Molecular Weight
889.95
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS9424051-01 0.02 mg
Recombinant Human mRNA-decapping enzyme 1A (DCP1A)
Sign In for Pricing
View Details MBS9424051-02 0.1 mg
Recombinant Human mRNA-decapping enzyme 1A (DCP1A)
Sign In for Pricing
View Details MBS9424051-03 1 mg
Recombinant Human mRNA-decapping enzyme 1A (DCP1A)
Sign In for Pricing
View Details MBS9424051-04 5x 1 mg
Recombinant Human mRNA-decapping enzyme 1A (DCP1A)
Sign In for Pricing
View Details 
T5400-18A-ML490 100 µL
Thyroid Stimulating Hormone, alpha (Thyroid-stimulating Hormone alpha Chain, TSH alpha, TSH A, TSHA, Thyrotropin alfa, Thyrotropin alpha Chain) (MaxLight 490)
Sign In for Pricing
View Details