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Mal-VC-PAB- (N-Me-amide-C3) -ADU-S100 triethylamine

Product Specifications

CAS Number

2249935-19-9

Target

Drug-Linker Conjugates for ADC, EGFR, STING

Related Pathways

Immunology/Inflammation, Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Antibody-drug Conjugate/ADC Related

Bioactivity

Mal-VC-PAB- (N-Me-amide-C3) -ADU-S100 triethylamine is a linker–payload small molecule of an immune-stimulating antibody conjugate (ISAC), consisting of the STING agonist (ADU-S100) and a cleavable linker. Mal-VC-PAB- (N-Me-amide-C3) -ADU-S100 triethylamine can be used in cancer research.

Smiles

CCN(CC)CC.[H][C@@]12COP(S)(=O)O[C@@]3([H])[C@@H](OC(=O)CCCN(C)C(=O)OCc4ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCN5C(=O)C=CC5=O)C(C)C)cc4)[C@@H](O[C@]3([H])COP(S)(=O)O[C@]([H])([C@@H]1O)[C@@H](O2)n1cnc2c(N)ncnc12)n1cnc2c(N)ncnc12

Molecular Formula

C51H65N17O19P2S2.xC6H15N

Molecular Weight

1447.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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