U7D-1
Product Specifications
Target
Apoptosis, PROTACs, MDM-2/p53, DUB
Related Pathways
Apoptosis, PROTAC, Cell Cycle/Checkpoint, Ubiquitination, DNA Damage/DNA Repair
Bioactivity
U7D-1, a groundbreaking and selective ubiquitin-specific protease 7 (USP7) PROTAC degrader, exhibits a DC50 value of 33 nM in RS4;11 cells, demonstrating its potent anticancer properties. Furthermore, U7D-1 effectively induces apoptosis in Jeko-1 cells [1].
Molecular Formula
C53H65N9O7
Molecular Weight
940.14
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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