KTX-951
Product Specifications
CAS Number
2573298-36-7
Target
IRAK, PROTACs
Related Pathways
Immunology/Inflammation, NF-κB, PROTAC
Bioactivity
KTX-951, a PROTAC designed for IRAK4 degradation (DC 50 =18 nM), exhibits an oral bioavailability (F%) of 22% in a rat model at a dosage of 10 mg/kg. Additionally, KTX-951 demonstrates promising anticancer potential [1].
Smiles
COc1cc2nn(cc2cc1NC(=O)c1cccc(n1)C(C)(F)F)[C@H]1CC[C@H](CN2CCC3(CC(CCNc4cccc5C(=O)N(C6CCC(=O)NC6=O)C(=O)c45)C3)CC2)CC1
Molecular Formula
C46H52F2N8O6
Molecular Weight
850.95
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
bs-106604P-01 20 µg
Recombinant Influenza B virus (Flu B) HA/Hemagglutinin Protein, C-His
Sign In for Pricing
View Details bs-106604P-02 50 µg
Recombinant Influenza B virus (Flu B) HA/Hemagglutinin Protein, C-His
Sign In for Pricing
View Details 
MBS7098186 Inquire
Recombinant Lotus japonicus NAD (P)H-quinone oxidoreductase subunit 5, chloroplastic (ndhF), partial
Sign In for Pricing
View Details 
MBS7075289 Inquire
Recombinant Caenorhabditis elegans Protein unc-1 (unc-1), partial
Sign In for Pricing
View Details