KTX-951
Product Specifications
CAS Number
2573298-36-7
Target
IRAK|||PROTACs
Related Pathways
Immunology/Inflammation|||NF-?B|||PROTAC
Bioactivity
KTX-951, a PROTAC designed for IRAK4 degradation (DC 50 =18 nM), exhibits an oral bioavailability (F%) of 22% in a rat model at a dosage of 10 mg/kg. Additionally, KTX-951 demonstrates promising anticancer potential [1].
Smiles
COc1cc2nn(cc2cc1NC(=O)c1cccc(n1)C(C)(F)F)[C@H]1CC[C@H](CN2CCC3(CC(CCNc4cccc5C(=O)N(C6CCC(=O)NC6=O)C(=O)c45)C3)CC2)CC1
Molecular Formula
C46H52F2N8O6
Molecular Weight
850.95
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
036589-HRP 200 µL
HIST1H2AK, NT (HIST1H2AG, H2AFP, Histone H2A type 1, Histone H2A/p) (Azide free) (HRP) discontinued
Ask
View Details 