M4K2234
Product Specifications
CAS Number
2421141-51-5
Target
ALK
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9999
Bioactivity
M4K2234 (Compound 26b) is a selective inhibitor of ALK2, displaying IC50 values of 5 nM for ALK2 and 2144 nM for ALK5. As a chemical probe for ALK1 and ALK2 kinases, it is used in mechanistic studies of BMP signaling and in cancer research where dysregulated ALK2 activity is implicated. Its high selectivity profile supports targeted investigations into ALK-mediated pathways.
Smiles
O=C(N)C1=C(F)C=C(C=C1OC)C2=CN=CC(C3=CC=C(C=C3)N4CCN(CC4)C(C)C)=C2C
Molecular Formula
C27H31FN4O2
Molecular Weight
462.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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