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TAM470

Product Specifications

Target

Microtubule Associated|||ADC Cytotoxin

Related Pathways

Cytoskeletal Signaling|||Antibody-drug Conjugate/ADC Related

Bioactivity

TAM470, a novel cytolysin, inhibits both tubulin polymerization and microtubule depolymerization. It serves as a precursor in the synthesis of OMTX705, a payload molecule. OMTX705 represents a new class of FAP-targeting antibody-drug conjugates (ADCs) exhibiting antitumor activity [1].

Smiles

CCCO[C@H](C[C@H](C(C)C)N(CCC)C(=O)[C@@H](NC(=O)[C@H]1CCCCN1C)[C@@H](C)CC)c1nc(cs1)C(=O)N[C@H](C[C@H](C)C(=O)NN)Cc1ccc(O)cc1

Molecular Formula

C41H67N7O6S

Molecular Weight

786.08

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/64416078658273334/T74648

CAS Number

1802498-63-0

Available Sizes

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