TAM470
Product Specifications
CAS Number
1802498-63-0
Target
Microtubule Associated, ADC Cytotoxin
Related Pathways
Cytoskeletal Signaling, Antibody-drug Conjugate/ADC Related
Bioactivity
TAM470, a novel cytolysin, inhibits both tubulin polymerization and microtubule depolymerization. It serves as a precursor in the synthesis of OMTX705, a payload molecule. OMTX705 represents a new class of FAP-targeting antibody-drug conjugates (ADCs) exhibiting antitumor activity [1].
Smiles
CCCO[C@H](C[C@H](C(C)C)N(CCC)C(=O)[C@@H](NC(=O)[C@H]1CCCCN1C)[C@@H](C)CC)c1nc(cs1)C(=O)N[C@H](C[C@H](C)C(=O)NN)Cc1ccc(O)cc1
Molecular Formula
C41H67N7O6S
Molecular Weight
786.08
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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