What is the catalog number for DB1113?

The catalog number for DB1113 is T74642.

What sizes are available for DB1113?

DB1113 is available in the following size(s): 5 mg, 50 mg.

How many pack sizes does DB1113 come in?

DB1113 is available in 2 different pack sizes.

DB1113 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures DB1113?

DB1113 is manufactured by Molfinity.

What is the estimated delivery time for DB1113?

Estimated delivery time for DB1113 is approximately 10 business day(s), depending on your location.

DB1113

Product Specifications

CAS Number

2769753-53-7

Target

PROTACs, Ferroptosis, LIM Kinase, Autophagy, MAPK, Serine/threonin kinase, CDK, SIK, Bcr-Abl

Related Pathways

Autophagy, Angiogenesis, MAPK, PI3K/Akt/mTOR signaling, Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint, Metabolism, Apoptosis, PROTAC, Cytoskeletal Signaling

Bioactivity

DB1113 (Example 24) is a bifunctional compound designed for the targeted degradation of various kinases, including ABL1, ABL2, BLK, CDK11B, CDK4, CSK, EPHA3, FER, GAK, LIMK1, MAP3K20, MAP4K1, MAP4K2, MAP4K3, MAP4K5, MAPK14, MAPK7, MAPK8, MAPK9, MAPKAPK2, MAPKAPK3, NLK, PDIK1L, PTK2B, RIPK1, RPS6KA1, RPS6KA3, SIK2, SIK3, STK35, TNK2, and ULK1. This capability positions DB1113 as a valuable tool for research into diseases or disorders associated with aberrant kinase activity [1].

Smiles

C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)CCCCN1CCN(CC1)c1ccc(Nc2ncc3CN(C(=O)N(C)c3n2)c2cc(NC(=O)c3cccc(c3)C(F)(F)F)ccc2C)cn1)C(C)(C)C)c1ccc(cc1)-c1scnc1C