XL01126
Product Specifications
Target
PROTACs, LRRK2
Related Pathways
Autophagy, PROTAC
Bioactivity
XL01126, a potent degrader of LRRK2, exhibits DC50 values of 14 nM (G2019S LRRK2) and 32 nM (WT LRRK2), respectively. It has the ability to cross the blood-brain barrier, making it a viable degrader probe for Parkinson's disease research. This compound is instrumental in exploring the non-catalytic and scaffolding functions of LRRK2 [1].
Molecular Formula
C50H64ClFN10O6S2
Molecular Weight
1019.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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