RNA polymerase II-IN-1
Product Specifications
CAS Number
2891451-07-1
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Bioactivity
RNA polymerase II-IN-1 (compound 19iv), an amatoxin, selectively inhibits RNA polymerase II (Pol II) with an IC50 of 36.66 nM and exhibits heightened cytotoxicity towards cancer cells while reducing toxicity in normal cells compared to ?-Amanitin [1].
Molecular Formula
C38H53N11O12S
Molecular Weight
887.96
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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