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NAMPT degrader-1

Product Specifications

Target

Autophagy, NAMPT, Others, ATTECs

Related Pathways

Others, Autophagy, PROTAC, Metabolism

Bioactivity

NAMPT Degrader-1 (Compound A3), a nicotinamide phosphoribosyltransferase (NAMPT) degrader, exhibits potent antitumor activity in cells by specifically inducing the degradation of NAMPT via the autophagy-lysosomal pathway, with an inhibitory concentration (IC50) of 0.023 μM [1].

Molecular Formula

C56H68ClN9O5S2

Molecular Weight

1046.78

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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