NAMPT degrader-1
Product Specifications
Target
Autophagy, NAMPT, Others, ATTECs
Related Pathways
Others, Autophagy, PROTAC, Metabolism
Bioactivity
NAMPT Degrader-1 (Compound A3), a nicotinamide phosphoribosyltransferase (NAMPT) degrader, exhibits potent antitumor activity in cells by specifically inducing the degradation of NAMPT via the autophagy-lysosomal pathway, with an inhibitory concentration (IC50) of 0.023 μM [1].
Molecular Formula
C56H68ClN9O5S2
Molecular Weight
1046.78
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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