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RIPK2-IN-2

Product Specifications

CAS Number

2143956-20-9

Target

Others, PROTACs, RIP kinase

Related Pathways

Others, NF-κB, PROTAC, Apoptosis

Bioactivity

RIPK2-IN-2 (example 25) is a RIP2 kinase PROTAC inhibitor that effectively blocks RIP2-dependent pro-inflammatory signaling and regulates RIP2 kinase activity in autoinflammatory diseases [1].

Smiles

CN[C@@H](C)C(=O)N[C@@H](C1CCN(CC1)C(=O)c1cnc(nc1)N1CCN(CCOc2cc3ncnc(Nc4n[nH]c(C)c4C)c3cc2S(=O)(=O)C(C)(C)C)CC1)C(=O)N1CCC[C@H]1c1nc(cs1)C(=O)c1ccc(F)cc1

Molecular Formula

C53H65FN14O7S2

Molecular Weight

1093.3

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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