DTAG-47
Product Specifications
CAS Number
2265886-81-3
Target
PROTACs, FKBP
Related Pathways
PROTAC, Apoptosis, Immunology/Inflammation, Autophagy
Bioactivity
DTAG-47, a heterobifunctional molecule, specifically targets the mutant FKBP12 (FKBP12 F36V), which functions as a degradation tag (dTAG) when fused to a protein of interest. This compound is utilized in the study of basal-like breast cancers (BBC) [1].
Smiles
CC[C@H](C(=O)N1CCCC[C@H]1C(=O)O[C@H](CCc1ccc(OC)c(OC)c1)c1ccccc1OCC(=O)NCCCCCCCCNc1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1)c1cc(OC)c(OC)c(OC)c1
Molecular Formula
C59H73N5O14
Molecular Weight
1076.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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