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SW2_152F

Product Specifications

Target

Histone Methyltransferase, Others

Related Pathways

Chromatin/Epigenetic, Others

Bioactivity

SW2_152F is a potent and selective inhibitor of the chromobox 2 chromodomain (CBX2 ChD), exhibiting a dissociation constant (K d) of 80 nM. It demonstrates 24-1000-fold greater selectivity for CBX2 ChD over other CBX paralogs in vitro [1].

Smiles

ClC1=CC(Cl)=CC(C(N[C@@H](CC2=CC=C(O)C(Cl)=C2)C(N[C@@H](C3CCCC3)C(N[C@H]([C@@H](C)CC)C(N[C@@H](CCCCN(CC)CC)C(N[C@@H](CO)C(NCC#C)=O)=O)=O)=O)=O)=O)=C1

Molecular Formula

C45H62Cl3N7O8

Molecular Weight

935.37

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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